منابع مشابه
A Review of the Factors Affecting the Proliferation of Neural Stem and Progenitor Cells
Neural stem cells are undifferentiated cells that are located in limited areas of central nervous system. These cells have proliferation and self-renew ability and can be differentiated into neurons and glial cells. Mature nerve cells do not have proliferative ability; and due to the limited number of nerve stem cells, injuries to the nervous system are not recoverable. The purpose of this revi...
متن کاملEffect of Neurotrophin-3 on Differentiation of Rat Hair Follicle Stem Cells into Neural Like Cells
Purpose: The aim of this study was to evaluate the effect of NT-3 on the decrease of the differentiation time of bulge stem cells of rat hair follicle from neuron like cells.Materials and Methods: The bulge region of the rat whisker was isolated from and cultured in DMEM/F12 supplemented with epidermal growth factor (EGF) in 3 groups for 7, 8 and 9 days .Then 10 ng/ml NT-3 was added to each gro...
متن کاملEffect of selegiline on neural stem cells differentiation: a possible role for neurotrophic factors
Objective(s): The stimulation of neural stem cells (NSCs) differentiation into neurons has attracted great attention in management of neurodegenerative disease and traumatic brain injury. It has been reported that selegiline could enhance the morphologic differentiation of embryonic stem cells. Therefore this study aimed to investigate the effects of selegiline on NSCs differentiation with focu...
متن کاملP111: Effect of Human Neural Stem Cells on Neural Hyperactivity in Kindeling Rat Models
The excessive electrical activity of neurons is reported in many diseases including: Parkinson's disease, Alzheimer's disease, and Epilepsy. Electrical overactivity in hippocampus accelerates the depletion of neural stem cell (NSC) and impairs the neurogenesis in hippocampus. It is believed that neurogenesis in hippocampus improves the cognitive functions. In this experiment, we use kindled mod...
متن کاملIn Vitro Differentiation of Neural Stem Cells into Noradrenergic-Like Cells
Neural stem cells (NSCs) as a heterogeneous multipotent and self- renewal population are found in different areas in the developing mammalian nervous system, as well as the sub-ventricular zone (SVZ) and the hippocampus of the adult brain. NSCs can give rise to neurons, astrocytes and oligodendrocytes. The aim of this study was to differentiate neural stem cells into noradrenergic–like cells in...
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ژورنال
عنوان ژورنال: Development
سال: 2006
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.02695